Our Journey with DUOBRII Lotion – Learning about DUOBRII Lotion from our Doctor

Disclosure: This shop has been compensated by Inmar, Inc. and Ortho Dermatologics. I am working with the makers of DUOBRII® (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, in 2021. All opinions are mine alone. #ad #AskForDUOBRII #DUOBRII

Trying to Treat our Plaque Psoriasis

By now, you’re all familiar with our journey to plaque psoriasis treatment with DUOBRII Lotion, from Ortho Dermatologics. 

Like over 8 million adults in the United States, my boyfriend and I both suffer from this condition in which skin cells build up and form scales and itchy, dry patches.

What is Plaque Psoriasis?

Psoriasis is an auto-immune disease in which patients shed their skin too quickly, causing dead skin cells to pile up on the surface. Normal skin cell turnover usually takes about a month, but for patients with psoriasis the turnover can happen in only a few days. The result is a chronic skin condition that causes raised, red or silvery, scaly patches (plaques) to appear on the skin.

It’s a common skin condition that develops in both men and women at equal rates – often first appearing between the ages of 15 and 35. Scientists differ on its exact cause, but genetics and the immune system play major roles in the development of psoriasis.

Every winter, we have flare-ups of psoriasis when it’s cold and dry outside. This makes vacations on a tropical beach far less enjoyable than I’d like! No one enjoys showing off a red rash or sores on your arms or legs!

Enter DUOBRII Lotion!

DUOBRII Lotion is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. DUOBRII Lotion is the first and only topical treatment for plaque psoriasis that contains both halobetasol propionate and tazarotene in one formula. DUOBRII Lotion is FDA approved.

Since DUOBRII Lotion is a prescription medicine, you need to make an appointment to talk with your doctor about DUOBRII Lotion to see if it is right for you. If so, you’ll be given a prescription and can start treatment. Whether you plan to discuss via tele-health, a phone call, or an in person visit, tell your doctor in detail about your condition and why you think DUOBRII Lotion may be right for you.

Visiting our Doctor to Discuss Potential Treatments

I had already researched extensively as to the best potential option to address our skin condition and DUOBRII Lotion seemed right for us. So we made an appointment with our doctor. We were able to visit our doctor in person here in Manhattan. We explained our skin condition, and the numerous remedies we have already tried. We also spoke about the triggers which cause flare-ups of our condition (such as cold, stress and infections) and mentioned that the condition tends to worsen in the wintertime. We mentioned our symptoms such as the plaques (scales or elevation, redness and itchiness) as well as how much plaque psoriasis affects our daily lives. We were also asked to state the places on our body where the plaques appear.

Our doctor mentioned the various types of treatment for plaque psoriasis, such as topical or oral treatments, and agreed that DUOBRII Lotion could be a good treatment for us. She noted that our condition is different from other types of psoriasis such as scalp, nail, or guttate psoriasis and that DUOBRII Lotion is a prescription medicine specifically meant to treat adults with plaque psoriasis.

I was happy to hear that, but I was still curious about how well the medication works. Our doctor explained that with DUOBRII Lotion, over 40% of patients had clear or almost clear skin at 8 weeks across 2 clinical studies. Some patients achieved clear or almost clear skin by 2, 4, or 6 weeks. She also mentioned that DUOBRII Lotion is a treatment that keeps on working even after you stop using it. Individual results may vary.

Answering our Questions about DUOBRII Lotion

I was also wondering what makes DUOBRII Lotion different from other treatments we have tried. Our doctor explained that DUOBRII Lotion is made of two well-known ingredients that work together to treat plaque psoriasis, while each ingredient reduces the side effects of the other. The strong anti-inflammatory agent (halobetasol propionate) works to clear plaques, while the vitamin A derivative (tazarotene) helps extend the clearing process even after stopping treatment. Tazarotene, one of the key ingredients in DUOBRII Lotion, has been shown to reduce skin thinning associated with corticosteroids. DUOBRII Lotion should not be used during pregnancy.

She also gave us some important reminders about the use of the medication: DUOBRII Lotion should be applied once a day, only until your psoriasis is under control. All other potent-to-superpotent steroids have time limits on use. Talk to your doctor if you experience side effects.

In the end, our doctor suggested we take some time to think it over and then let her know if we’d like a prescription for DUOBRII Lotion.

Our appointment was extremely informative and we’re happy to state that we’re now considering trying out DUOBRII Lotion for ourselves. 

Perhaps it is right for you, too? Don’t wait, find out if DUOBRII Lotion can help with your plaque psoriasis. Make an appointment to talk to your doctor today.

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy. 

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.

What should I avoid during treatment with DUOBRII?

  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.

DUOBRII may cause side effects, including:

  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Please click here for full Prescribing Information, including Patient Information. 


Disclosure: This is a sponsored post written by me, @lighttravelsfaster on behalf of Inmar, Inc. and Ortho Dermatologics.

~Eileen Rhein, esq. from @lighttravelsfaster

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